王泽峰（研究员）的个人简介
简历：工作经历：2014/9-至今,中国，中国科学院上海生命科学研究院，计算生物学研究所，研究员、所长2013/5-2014/9,美国，北卡罗来纳大学（教堂山），医学院药理系，副教授（终身教职）2007/1-2013/4,美国，北卡罗来纳大学（教堂山）医...基本内容
简历：工作经历：2014/9-至今,中国，中国科学院上海生命科学研究院，计算生物学研究所，研究员、所长2013/5-2014/9,美国，北卡罗来纳大学（教堂山），医学院药理系，副教授（终身教职）2007/1-2013/4,美国，北卡罗来纳大学（教堂山）医学院药理系，助理教授2002/9-2006/12,美国，麻省理工学院，生物系，博士后研究员教育经历：1997/09-2002/06,美国，约翰霍普金斯医学院，生化博士1994/09-1997/06,中国，中科院生物物理所，分子生物学硕士1991/09-1994/06,中国，清华大学,计算机工程与技术，工学学士1989/09-1994/06,中国，清华大学,生物科学与技术，理学学士研究方向：1）RNA可变剪接的机理2）RNA结合蛋白的合成生物学3）RNA功能基因组学职称：研究员职务：计算生物学研究所所长、研究组长、博士生导师获奖及荣誉：2012-2016 杰弗逊基础医学奖（Jefferson-Pilot Fellowships in Academic Medicine Award）2009-2011 Kimmel学者奖(Kimmel Scholar Award,)2008-2011 贝克曼青年学者奖(Beckman Young Investigator Award )2008-2010 斯隆研究奖(Alfred Sloan Research Fellow)2007 RNA 学会青年学者奖(RNA Society/Scaringe Young Scientist Award)2003-2006 Damon Runyon博士后研究奖2002Paul Ehrlich青年学者奖(Paul Ehrlich Research,Johns Hopkins University)1999Burroughs Wellcome奖学金(Burroughs Wellcome Fellowship)1996-1997中科院地奥奖学金1994清华大学优秀毕业生（生物系94年唯一优秀毕业生）1993-1994清华大学光华奖学金1990-1993清华大学优秀生奖学金代表论著：1. Tsai YS, Dominguez D, Gomez SM, and Wang Z*. Cancer-specific splicing events acrossmultiple tumors are closely associated with cell cycle regulation (2015) Oncotarget 6 (9),6825-68392. Wang Z*Not just a sponge: new functions of circular RNAs discovered (2015) Sci China Life Sci. 2015 Feb 14. [Epub ahead of print]3. Wang Y, Wang Z*. Efficient backsplicing produces translatable circularmRNAs. (2015)RNA Feb;21(2):172-9. doi: 10.1261/rna.048272.114. Epub 2014 Dec 1. PubMed PMID:25449546.4. Wang Y, Chen D, Qian H, Tsai YS, Shao S, Dominguez D and Wang Z*.RBM4 specifically controls alternative splicing to suppress tumor progression (2014) Cancer Cell 26(3):374-389.doi: 10.1016/j.ccr.2014.07.010.Highlighted by Research Watch article “RBM4-regulated alternative splicing suppresses tumorigenesis” Cancer Discovery 2014 Nov;4(11):1253. doi: 10.1158.5. Choudhury R and Wang Z*Manipulation of RNA using engineered proteins with customized specificity (2014) In: GW Yeo (ed.) System Biology of RNA Binding Proteins. Adv Exp Med Biol., 2014;825:199-225. doi: 10.1007/978-1-4939-1221-6_6.6. Tsai YS, Gomez SM, and Wang Z*. Prevalent RNA recognition motif duplication in the human genome. RNA (2014) May;20(5):702-12. doi: 10.1261/rna.044081.113.7. Choudhury R, Ghose Roy S, Tsai YS, Tripathy A , Graves LM and Wang Z*. The splicing activator DAZAP1 integrates splicing control into MEK/Erk regulated cell proliferation and migration. Nature Communications (2014); 5:3078. doi: 10.1038/ncomms4078.8. Matera AG and Wang Z*. Ribonucleoprotein assembly and dynamics: A day in the life of the spliceosome. Nature Review Molecular Cell Biology (2014) Apr;15(4):2949. Zhang W, Wang Y, Dong S, Choudhury R, Jin Y, and Wang Z*Treatment of type 1 Myotonic Dystrophy by engineering site-specific RNA endonucleases that target (CUG)n repeats. Molecular Therapy 2013 Oct 23. doi: 10.1038/mt.2013.251. [Epub ahead of print]10. Wang Y and Wang Z*Systematical identification of splicing regulatory cis-elements and cognate trans-factors (2013), Methods. Aug 22. doi:pii: S1046-2023(13)00326-5.11. Wang Y, Wang Z* and Hall TM* (co-corresponding author). Engineered proteins with PUF scaffold to manipulate RNA metabolism (2013). FEBS J. Jun 3. doi: 10.1111/febs.12367 invited review12. Wang Y, Xiao X, Zhang J, Choudhury R, Robertson A, Li K, Ma M, BurgeCB and Wang Z*. A complex network of factors with overlapping affinities control splicing repression by intronic elements. (2013) Nature Structure Molecular Biology Jan;20(1):36-45. doi: 10.1038/nsmb.2459. Epub 2012 Dec 16.13. Choudhury R, Dominguez D, Wang Y and Wang Z*. Engineering RNA endonucleases with customized sequence specificities (2012). Nature Communications Oct 23;3:1147. doi: 10.1038/ncomms2154.14. Wang Y, Ma M, Xiao XS and Wang Z*. Intronic splicing enhancers, cognate splicing factors and context dependent regulation rules. (2012) Nature Structure Molecular Biology,19(10):1044-52. doi: 10.1038/nsmb.2377. Epub 2012 Sep 1615. Dong S, Wang Y, Cassidy-Amstutz C, Lu G, Bigler R, Li C, Jezyk MR, Hall TM , Wang Z*. A specific and modular binding code for cytosine recognition in PUF domains. (2011) J Biol Chem. 2011 Jul 29;286(30):26732-42. Epub 2011 Jun 8.
Selected as the paper of the week by J Bio. Chem.Recommended by an editorial comment in Chem Biol. 2011 Jul 29;18 (7):821-3.16. Abbas AI, Urban DJ, Jensen NH, Farrell MS, Kroeze WK, Mieczkowski P, Wang Z, Roth BL. Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method. (2010) Nucleic Acids Res. 38(10):e118. Epub 2010 Feb 25.17. Burd CE, Jeck WR, Liu Y, Sanoff HK, Wang Z, Sharpless NE. Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk. (2010) PloS Genet, 6(12):e1001233.
